Lung cancers
TRIAL NAME: CONCORDE
Brief title/summary
A platform study of DNA damage response inhibitors in combination with conventional radiotherapy in non-small cell lung cancer.
Where is the trial open
Northern Centre for Cancer Care
TRIAL NAME: Pacific 8
Brief title/summary
This trial is looking at durvalumab and domvanalimab for non small cell lung cancer that has grown into surrounding tissues. It is for people with non small cell lung cancer that is locally advanced, can’t be removed by surgery and hasn’t got worse following chemoradiotherapy.
Where is the trial open
Northern Centre for Cancer Care
TRIAL NAME: Stablemates
Brief title/summary
This study is comparing a method of surgery (JoLT-Ca Sublobar Resection) against a modern form of radiotherapy (Stereotactic Ablative Radiotherapy) as a treatment for lung cancer.
Where is the trial open
The James Cook University Hospital
Link to further information
Skin cancers
TRIAL NAME: SCC- After
Brief title/summary
The SCC-AFTER research study aims to find out whether it is better to use radiotherapy or not to prevent high-risk skin cancer from coming back after it has been removed by surgery.
Where is the trial open
The James Cook University Hospital
Link to further information
Urological cancers
TRIAL NAME: PEARLS
Brief title/summary
A trial of intensity modulated radiotherapy to treat prostate cancer. This trial is looking at radiotherapy to nearby lymph nodes in addition to radiotherapy to the prostate. It is open to men having radiotherapy for the first time.
Where is the trial open
Northern Centre for Cancer Care
TRIAL NAME: Pointer-PC
Brief title/summary
Pelvis Or Involved Node Treatment: Eradicating Recurrence in Prostate Cancer (POINTER-PC). This trial will explore how radiotherapy can be made more effective for men whose cancer has come back following an initial course of treatment intended to cure it.
Where is the trial open
The James Cook University Hospital
Link to further information
TRIAL NAME: STAMPEDE-2
Brief title/summary
STAMPEDE2 is a clinical trial testing new treatments in men with prostate cancer that has spread to other parts of the body (metastatic prostate cancer). It tests these treatments when the cancer is hormone-sensitive, which means that it is at a stage where it is responsive to treatment with hormone therapy.
Where is the trial open
The James Cook University Hospital
Link to further information
Other/Multiple tumour sites
TRIAL NAME: FaR-RMS
Brief title/summary
This trial is looking at new ways of treating rhabdomyosarcoma in children and adults. Rhabdomyosarcoma is a type of soft tissue sarcoma. The main aims of the trial are to improve treatment outcomes and quality of life.
Where is the trial open
Northern Centre for Cancer Care
TRIAL NAME: iPREDICT
Brief title/summary
The purpose of this study is to learn more about personalised cancer therapy including response to treatment and side effects. Information from the patient's medical record regarding the tests and treatments they have received, or will receive, for their cancer will be collected. Genomic testing on tissue from the primary tumour or metastases will be used to match therapy recommendations.
Where is the trial open
Northern Centre for Cancer Care
Link to further information
TRIAL NAME: PROTIS
Brief title/summary
The purpose of this study is to assess whether PBT (proton beam therapy) improves disease-free survival rate compared with standard-of-care IMRT (intensity modulated radiotherapy) for nose and sinus cancer which has not spread. This trial will compare the cure rates and side effects of the two treatments.
Participants have a 50:50 chance of receiving IMRT at a local hospital, or PBT at one of the UK proton centres (Manchester or London).
Delivery of radiotherapy will happen over 6-7 weeks.
Where is the trial open
The James Cook University Hospital
Link to further information
Freeman Hospital, Freeman Rd, Newcastle Upon Tyne, England NE7 7DN, United Kingdom.