find a clinical trial
Do you want to find out about radiotherapy clinical trials in the network?
Below is a list of open radiotherapy clinical trials.
Trials are not available at all radiotherapy centres, and patients will not be eligible for every trial. This is due to the eligibility and exclusion criteria, which is set by the trial design team.
Please speak to your clinical team if you have any questions about clinical trials.
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Brain tumours
TRIAL NAME: APPROACH
Brief title/summary
The APPROACH (analysis of Proton vs. Photon Radiotherapy in Oligodendroglioma and Assessment of Cognitive Health) is comparing standard radiotherapy with proton beam therapy for adults with oligodendroglioma. The researchers aim to improve long term side effects of treatment.
Where is the trial open
James Cook University Hospital
TRIAL NAME: Brioche
Brief title/summary
A trial looking at re-irradiation and chemotherapy in patients with recurrent glioblastoma.
Where is the trial open
The James Cook University Hospital
Link to further information
TRIAL NAME: PARADIGM
Brief title/summary
This trial is looking at whether a drug called olaparib improves the way radiotherapy and chemotherapy work. It is for people with a type of brain tumour called glioblastoma who are newly diagnosed and have recently had surgery.
Where is the trial open
The Northern Centre for Cancer Care
TRIAL NAME: SIOP EP II
Brief title/summary
Prospective trial for the diagnosis and treatment of children, adolescents and young adults with Intracranial Germ Cell Tumours. The overall aim of this project is to improve the outcome of patients diagnosed with ependymoma by improving and harmonising the staging and the standard of care of this patient population and to improve the investigators understanding of the underlying biology thereby informing future treatment.
Where is the trial open
The Northern Centre for Cancer Care
Link to further information
TRIAL NAME: SIOP High-Risk Medulloblastoma (HRMB)
Brief title/summary
A trial comparing treatments for high-risk medulloblastoma (HR-MB). The aims of this trial are to compare these treatments to find out which is the best treatment for high risk medulloblastoma, what the long term side effects are and what affect the treatments have on quality of life.
Where is the trial open
The Northern Centre for Cancer Care
Breast cancers
TRIAL NAME: ATNEC
Brief title/summary
A trial looking at further treatment to the armpit after surgery to remove breast cancer.
Where is the trial open
The James Cook University Hospital
The Northern Centre for Cancer Care
TRIAL NAME: PARABLE
Brief title/summary
Proton beam therapy in patients with breast cancer: evaluating early and late effects. This trial is looking at proton beam therapy for people with breast cancer. It is for people who have an increased risk of developing long term heart problems years after radiotherapy.
Where is the trial open
The James Cook University Hospital
The Northern Centre for Cancer Care
TRIAL NAME: SMALL
Brief title/summary
This trial is comparing surgery with vacuum assisted excision for small early breast cancers. It is for women taking part in the NHS breast screening programme, and who had a small early breast cancer found during their screening.
Where is the trial open
The Northern Centre for Cancer Care
Head and neck cancers
TRIAL NAME: LARCH
Brief title/summary
LARyngeal Cancer coHort (LARCH) aims to establish how survival and quality-of-life outcomes compare between surgery and (chemo)radiotherapy in early and advanced laryngeal cancer.
Where is the trial open
The James Cook University Hospital
The Northern Centre for Cancer Care
Lung cancers
TRIAL NAME: CONCORDE
Brief title/summary
A platform study of DNA damage response inhibitors in combination with conventional radiotherapy in non-small cell lung cancer.
Where is the trial open
Northern Centre for Cancer Care
TRIAL NAME: Pacific 8
Brief title/summary
This trial is looking at durvalumab and domvanalimab for non small cell lung cancer that has grown into surrounding tissues. It is for people with non small cell lung cancer that is locally advanced, can’t be removed by surgery and hasn’t got worse following chemoradiotherapy.
Where is the trial open
Northern Centre for Cancer Care
TRIAL NAME: Stablemates
Brief title/summary
This study is comparing a method of surgery (JoLT-Ca Sublobar Resection) against a modern form of radiotherapy (Stereotactic Ablative Radiotherapy) as a treatment for lung cancer.
Where is the trial open
The James Cook University Hospital
Link to further information
Skin cancers
TRIAL NAME: SCC- After
Brief title/summary
The SCC-AFTER research study aims to find out whether it is better to use radiotherapy or not to prevent high-risk skin cancer from coming back after it has been removed by surgery.
Where is the trial open
The James Cook University Hospital
Northern Centre for Cancer Care
Link to further information
Urological cancers
TRIAL NAME: PACE- NODES
Brief title/summary
A trial looking at stereotactic body radiotherapy for prostate cancer. This trial is comparing stereotactic body radiotherapy to the prostate with stereotactic body radiotherapy to the prostate and lymph nodes in the pelvis. It is open to people with prostate cancer that has a high risk of the cancer coming back.
Where is the trial open
The James Cook University Hospital
Northern Centre for Cancer Care
TRIAL NAME: PEARLS
Brief title/summary
A trial of intensity modulated radiotherapy to treat prostate cancer. This trial is looking at radiotherapy to nearby lymph nodes in addition to radiotherapy to the prostate. It is open to men having radiotherapy for the first time.
Where is the trial open
Northern Centre for Cancer Care
TRIAL NAME: Pointer-PC
Brief title/summary
Pelvis Or Involved Node Treatment: Eradicating Recurrence in Prostate Cancer (POINTER-PC). This trial will explore how radiotherapy can be made more effective for men whose cancer has come back following an initial course of treatment intended to cure it.
Where is the trial open
The James Cook University Hospital
Link to further information
TRIAL NAME: STAMPEDE-2
Brief title/summary
STAMPEDE2 is a clinical trial testing new treatments in men with prostate cancer that has spread to other parts of the body (metastatic prostate cancer). It tests these treatments when the cancer is hormone-sensitive, which means that it is at a stage where it is responsive to treatment with hormone therapy.
Where is the trial open
The James Cook University Hospital
Link to further information
Freeman Hospital, Freeman Rd, Newcastle Upon Tyne, England NE7 7DN, United Kingdom.