Below is a list of open radiotherapy clinical trials.
Trials are not available at all radiotherapy centres, and patients will not be eligible for every trial. This is due to the eligibility and exclusion criteria, which is set by the trial design team.
Please speak to your clinical team if you have any questions about clinical trials.
For health professionals only:
Please help us keep this information up to date by notifying us of any changes.
The APPROACH (analysis of Proton vs. Photon Radiotherapy in Oligodendroglioma and Assessment of Cognitive Health) is comparing standard radiotherapy with proton beam therapy for adults with oligodendroglioma. The researchers aim to improve long term side effects of treatment.
James Cook University Hospital
A trial looking at re-irradiation and chemotherapy in patients with recurrent glioblastoma.
The James Cook University Hospital
This trial is looking at whether a drug called olaparib improves the way radiotherapy and chemotherapy work. It is for people with a type of brain tumour called glioblastoma who are newly diagnosed and have recently had surgery.
The Northern Centre for Cancer Care
Prospective trial for the diagnosis and treatment of children, adolescents and young adults with Intracranial Germ Cell Tumours. The overall aim of this project is to improve the outcome of patients diagnosed with ependymoma by improving and harmonising the staging and the standard of care of this patient population and to improve the investigators understanding of the underlying biology thereby informing future treatment.
The Northern Centre for Cancer Care
A trial comparing treatments for high-risk medulloblastoma (HR-MB). The aims of this trial are to compare these treatments to find out which is the best treatment for high risk medulloblastoma, what the long term side effects are and what affect the treatments have on quality of life.
The Northern Centre for Cancer Care
A trial looking at further treatment to the armpit after surgery to remove breast cancer.
The James Cook University Hospital
The Northern Centre for Cancer Care
Proton beam therapy in patients with breast cancer: evaluating early and late effects. This trial is looking at proton beam therapy for people with breast cancer. It is for people who have an increased risk of developing long term heart problems years after radiotherapy.
The James Cook University Hospital
The Northern Centre for Cancer Care
This trial is comparing surgery with vacuum assisted excision for small early breast cancers. It is for women taking part in the NHS breast screening programme, and who had a small early breast cancer found during their screening.
The Northern Centre for Cancer Care
LARyngeal Cancer coHort (LARCH) aims to establish how survival and quality-of-life outcomes compare between surgery and (chemo)radiotherapy in early and advanced laryngeal cancer.
The James Cook University Hospital
The Northern Centre for Cancer Care
A platform study of DNA damage response inhibitors in combination with conventional radiotherapy in non-small cell lung cancer.
Northern Centre for Cancer Care
This trial is looking at durvalumab and domvanalimab for non small cell lung cancer that has grown into surrounding tissues. It is for people with non small cell lung cancer that is locally advanced, can’t be removed by surgery and hasn’t got worse following chemoradiotherapy.
Northern Centre for Cancer Care
This study is comparing a method of surgery (JoLT-Ca Sublobar Resection) against a modern form of radiotherapy (Stereotactic Ablative Radiotherapy) as a treatment for lung cancer.
The James Cook University Hospital
A trial looking at stereotactic body radiotherapy for prostate cancer. This trial is comparing stereotactic body radiotherapy to the prostate with stereotactic body radiotherapy to the prostate and lymph nodes in the pelvis. It is open to people with prostate cancer that has a high risk of the cancer coming back.
The James Cook University Hospital
Northern Centre for Cancer Care
A trial of intensity modulated radiotherapy to treat prostate cancer. This trial is looking at radiotherapy to nearby lymph nodes in addition to radiotherapy to the prostate. It is open to men having radiotherapy for the first time.
Northern Centre for Cancer Care
Pelvis Or Involved Node Treatment: Eradicating Recurrence in Prostate Cancer (POINTER-PC). This trial will explore how radiotherapy can be made more effective for men whose cancer has come back following an initial course of treatment intended to cure it.
The James Cook University Hospital
STAMPEDE2 is a clinical trial testing new treatments in men with prostate cancer that has spread to other parts of the body (metastatic prostate cancer). It tests these treatments when the cancer is hormone-sensitive, which means that it is at a stage where it is responsive to treatment with hormone therapy.
The James Cook University Hospital
Freeman Hospital, Freeman Rd, Newcastle Upon Tyne, England NE7 7DN, United Kingdom.
