Below is a list of open radiotherapy clinical trials.
Trials are not available at all radiotherapy centres, and patients will not be eligible for every trial. This is due to the eligibility and exclusion criteria, which is set by the trial design team.
Please speak to your clinical team if you have any questions about clinical trials.
For health professionals only:
Please help us keep this information up to date by notifying us of any changes.
The APPROACH (analysis of Proton vs. Photon Radiotherapy in Oligodendroglioma and Assessment of Cognitive Health) is comparing standard radiotherapy with proton beam therapy for adults with oligodendroglioma. The researchers aim to improve long term side effects of treatment.
James Cook University Hospital
Prospective trial for the diagnosis and treatment of children, adolescents and young adults with Intracranial Germ Cell Tumours. The overall aim of this project is to improve the outcome of patients diagnosed with ependymoma by improving and harmonising the staging and the standard of care of this patient population and to improve the investigators understanding of the underlying biology thereby informing future treatment.
The Northern Centre for Cancer Care
A trial comparing treatments for high-risk medulloblastoma (HR-MB). The aims of this trial are to compare these treatments to find out which is the best treatment for high risk medulloblastoma, what the long term side effects are and what affect the treatments have on quality of life.
The Northern Centre for Cancer Care
A trial looking at further treatment to the armpit after surgery to remove breast cancer.
The James Cook University Hospital
The Northern Centre for Cancer Care
A randomised clinical trial testing a 1-week schedule of curative simultaneous integrated boost (SIB) radiotherapy against a standard 3-week schedule in patients with early breast cancer.
The James Cook University Hospital
Proton beam therapy in patients with breast cancer: evaluating early and late effects. This trial is looking at proton beam therapy for people with breast cancer. It is for people who have an increased risk of developing long term heart problems years after radiotherapy.
The James Cook University Hospital
The Northern Centre for Cancer Care
This trial is comparing surgery with vacuum assisted excision for small early breast cancers. It is for women taking part in the NHS breast screening programme, and who had a small early breast cancer found during their screening.
The Northern Centre for Cancer Care
The Artemis (Augmenting Radiotherapy in Rectal Cancer to Minimise Invasive Surgery) trial is for patients who have been diagnosed as having a cancer of the lower bowel, known as the rectum. This study will examine the benefit of adding an additional treatment alongside radiotherapy and chemotherapy with the hope of increasing the chance of curing rectal cancer without the need for surgery.
The Northern Centre for Cancer Care
County Durham and Darlington NHS FT
Colorectal symptoms after pelvic radiotherapy: understanding radiation proctopathy in cancer survivors. The aim of this study is to investigate the experiences and management of bowel symptoms among cancer survivors, including impact on daily life and experiences of seeking, accessing and providing support and treatment.
The Northern Centre for Cancer Care
GRACE (Gynae Radiotherapy Consent Enhancement) is a research collaboration between Lancaster and Bangor Universities. GRACE will improve how people make decisions about consent for radiotherapy for gynaecological cancers. This trial is open to patients who have been offered radiotherapy treatment, regardless of whether they accepted or declined treatment.
James Cook University Hospital
LARyngeal Cancer coHort (LARCH) aims to establish how survival and quality-of-life outcomes compare between surgery and (chemo)radiotherapy in early and advanced laryngeal cancer.
The James Cook University Hospital
The Northern Centre for Cancer Care
Freeman Hospital, Freeman Rd, Newcastle Upon Tyne, England NE7 7DN, United Kingdom.